Architectural Frame Work for Homology Modeling in Grid Environment
نویسندگان
چکیده
This paper shows how homology modeling works for given protein sequence and how it is implemented in grid environment. Homology modeling involves taking a known sequence with an unknown structure and mapping against a known structure of one or several similar protein. The quality of homology modeling is dependent on the quality of the sequence alignment and template structure. Based on this modeling, the unknown protein sequence can be predicted based on the relevance match found from the database. This homology modeling is very useful for molecular docking process. The number of sequences is inputted to the grid environment where homology modeling is designed by FCFS strategy.
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